Vattikuti Foundations has been involved in many philanthropic activities since 1997. These activities are mainly in the area of healthcare and poverty alleviation.
The foundation has distinguished itself by founding the Vattikuti Urology Institute at Henry Ford Hospitals and the Vattikuti Digital Breast Diagnostic Center at Beaumont Hospitals. This grant to these two institutions is one of the largest philanthropic contributions for medical care and research ever in the state of Michigan. To date the foundation has disbursed over $17.8 million to various causes.