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Cancer Therapy Researchers Uncover Cancer Cell-killer

04 November 2024

A team from the Broad Institute of MIT and Harvard in collaboration from Industry leaders Bayer and Trueline Therapeutics, have developed a 'small molecule drug' labeled BRD-810. BRD-810 inhibits a protein called MCL1, which blocks apoptosis, or programmed cell death- a natural process- within many types of cancer cells.

Over 10-years of research at the Broad Institute have contributed to the development of BRD-810. Online news service MedicalXpress reports that "...BRD-810 that holds promise as a therapeutic candidate for cancer. This small molecule reactivates the apoptosis cascade in tumor cells while sparing healthy cells in animal models."*

The compound is eliminated from animal models bodies in about 4-hours, thus causing few, if any harmful side effects, according to the reports.

To read the complete MedicalXpress report, please use this link: *https://medicalxpress.com/news/2024-10-small-molecule-drug-triggers-rapid.html

The open access nature cancer journal article can be access here: https://www.nature.com/articles/s43018-024-00814-0